Protective assessment of Euphorbia neriifolia and its isolated flavonoid against N-nitrosodiethylamine-induced hepatic carcinogenesis in male mice: A histopathological analysis
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چکیده
منابع مشابه
Chemoprevention by Euphorbia Neriifolia of DENA-induced Mouse Renal Carcinogenesis
Kidney cancer is the third most common malignancy of the genitourinary system account for 2 to 3 % of all cancers in men worldwide, with 130,000 new cases and 63,000 deaths from the disease occurring annually (Ferlay et al., 2004). Certain toxic chemicals and medicines can cause renal damage, are recognized as a toxicological problem. NNitrosodiethylamine (DENA) is the most important environmen...
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The objective of the present study was to investigate the hepatoprotective activity of methanol extract of Euphorbia neriifolia (MEEN) against paracetamol induced hepatotoxicity. Hepatotoxicity was induced in Wistar rats by oral administration of paracetamol (640 mg/kg suspended in 1% carboxy methyl cellulose), once during the 16 days treatment period. MEEN was administered orally at the doses ...
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ژورنال
عنوان ژورنال: Toxicology International
سال: 2014
ISSN: 0971-6580
DOI: 10.4103/0971-6580.128790